The PFL 2 mixed martial arts event for the 2019 season of the Professional Fighters League was held on May 23, 2019, at the Nassau Coliseum in Uniondale, New York.

This was the second regular season event of 2019 and included fights in the featherweight and lightweight divisions.

[2] Ramsey Nijem was expected to face Ronys Torres at this event.

However, Torres failed his medical tests prior to the weigh-ins and the bout was cancelled.

[2] The point system consists of outcome based scoring and bonuses for an early win.