The PFL 7 mixed martial arts event for the 2019 season of the Professional Fighters League was held on October 11, 2019, at the Mandalay Bay Events Center in Las Vegas, Nevada.

The event was the seventh of the 2019 season and marked the start of the playoffs for the Welterweight and Women's Lightweight divisions.

[1] Kayla Harrison was initially scheduled to face Genah Fabian at this event.

*Magomed Magomedkerimov was originally scheduled to face Ray Cooper III but was unable to continue in the tournament.

[2] * Genah Fabian was originally scheduled to face Kayla Harrison but was forced to pull out of the bout.