This protein is a ribonuclease that localizes to the nucleus and functions in pre-RNA processing.

[7] POP1 is also an autoantigen in patients with connective tissue diseases.

Mutations in the POP1 gene result in severe anauxetic dysplasia.

[9] This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 8 is a stub.