550019046ENSG00000213639ENSMUSG00000014956P62140P62141NM_206877NM_002709NM_206876NM_172707NP_002700NP_996759NP_766295Serine/threonine-protein phosphatase PP1-beta catalytic subunit is an enzyme that in humans is encoded by the PPP1CB gene.

PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription.

Mouse studies suggest that PP1 functions as a suppressor of learning and memory.

Two alternatively spliced transcript variants encoding distinct isoforms have been observed.

[6] PPP1CB has been shown to interact with PPP1R15A,[7][8] Nucleolin,[9] SMARCB1[7] and PPP1R9B.