[5][6][7] This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases.

It is active on peptide linkages involving the carboxyl group of lysine or arginine.

The protein is implicated in epithelial sodium channel regulation[8] and may help regulate a variety of tissue functions that involve a sodium channel.

[10][unreliable medical source] Chen LM, Hatfield ML, Fu YY, Chai KX.

Prostasin regulates iNOS and cyclin D1 expression by modulating protease-activated receptor-2 signaling in prostate epithelial cells.