Paenemarmota is an extinct genus of ground squirrel from North America.

Fossils are known from the Blancan and Hemphillian age from localities in the United States (Nebraska, Kansas, Texas, Arizona) and Mexico.

At around the size of a beaver, Paenemarmota is the largest known member of the squirrel family.

[2] Although some of its features are primitive, in general morphology it resembles the ground squirrels of the genus Spermophilus.

The large fourth premolars are exceptions to the general evolutionary trend in the ground squirrels and only in Paenemarmota and the living Marmota are these teeth larger than the first molars.