The commonly called Palace of the Dukes of Medinaceli (Spanish: Palacio de los Duques de Medinaceli) is a Renaissance palace located in Cogolludo, Spain, and is one of the most ancient sites of the region.

The palace of the marquises of Cogolludo is a gem of pure Spanish renaissance architecture, constructed between c. 1480 and 1502.

[4] It was declared Bien de Interés Cultural (historical and architectural landmark) in 1931.

Visitors are allowed into the interior of the building; but must do so with a tour guide managed by the tourist office.

[6] It dates from the 15th century, when Cogolludo was occupied by the Valterra family, who moved in to the place in 1404.