Palazzo de Felice (Italian for Palace of the de Felice) is an 18th-century palace in Grottaglie, Province of Taranto Apulia.

It is an ancestral home of the de Felice family.

The palace is located in the centre of Grottaglie, in the Piazza Santa Lucia.

[1] It is built in the baroque style of the day, boasting an imposing entrance of Corinthian columns, a balcony and a porch.

It was acquired by the town in the late 1980s, and now houses an art gallery, which opened in 2006.