Palazzo Malipiero-Trevisan is a Renaissance palace in Venice, Italy located in the Castello district, on the south-eastern side of campo Santa Maria Formosa and separated from it by the Santa Maria Formosa river (entry is through a private bridge).

Perhaps on this occasion it was rebuilt in its present form; the project was for a long time attributed, without certain proof, to Sante Lombardo who, more likely, was only concerned with finishing its decoration.

As time passed, the palazzo was divided in several properties, where the Diedo, the Bembo, and the Zen families lived, in addition to the Trevisans themselves.

The setting of the symmetrical façade, which still preserves the original Istrian stone roof, is typically of the Venetian Renaissance architectural style.

To embellish and regulate the parts of the façade, there are niches and marble discs—the latter recalling the Gothic-Byzantine style typical for the nearby Palazzo Vitturi.