The original stock exchange of Milan was established in 1808 in the seat of the Mount of Piety of the city.

The following year it was moved to the Palazzo dei Giureconsulti, in Piazza Mercanti, and at the beginning of the 20th century it was relocated again in a newly constructed building in Piazza Cordusio; this building now houses the headquarters of the Poste Italiane postal service, and has thus been renamed Palazzo della Posta ("Post Palace").

At its inauguration, it qualified as the most technologically advanced building in Italy; it was the first building to implement a single call button controlling several elevators, it had air conditioning, and housed the largest electric display of the times (in Italy) where stock quotations where updated in real-time.

The building has a monumental, 36 m high facade, in a style that mixes 20th-century architecture and Neoclassicism; it is realized in marble and travertine and decorated with sculptures by Leone Lodi and Geminiano Cibau.

The main room of the Palace, called "sala delle grida" ("cries room") as businessmen would shout their offers to buy and sell, is lighted by a large net, affixed to the ceiling, which reproduces the constellations in the celestial sphere.