In the early 18th century, the architect Girolamo Frigimelica Roberti continued restructuring and expansion, creating towards the Campo one of the most ostentatious private palace facades in the city.
In the atrium is a large ship lamp with three windows, il fanò, which was located on the quarterdeck of the galley of Andrea Pisani, once admiral of the Venetian fleet.
On the piano nobile, the portego, or entrance hall spans from the Campo to the Rio del Santissimo, and once displayed portraits of the Pisani family.
An inventory in 1809 of the other rooms of the palace catalogued 159 paintings, including works by Titian, Tintoretto, Paolo Veronese, and Palma il Vecchio.
Between 1897 and 1921 the City of Venice gradually became the sole owner of the building that housed the Liceo Società Musicale Benedetto Marcello, in the wing that faces the second courtyard, until in 1940, the palace was reserved for use exclusive of the Conservatory.