Palazzo Priuli Ruzzini Loredan, also called Palazzo Loredan at Campo Santa Maria Formosa, is a late 16th-century palace located at Campo Santa Maria Formosa in the Castello district of Venice, northern Italy, characterised by features of Renaissance and Baroque-style architecture on its façades.

The Palazzo was built as a noble residence of the Ruzzini in the late sixteenth century, a project attributed to architect Bartolomeo Manopola.

Carlo Ruzzini, 113th doge of the Republic of Venice, also belonged to this family, divided into numerous branches: a talented diplomat, Venetian ambassador to the main European courts (Spain, Vienna, Constantinople), he ascended to the ducal throne in 1732.

The building, which at the beginning of the 21st century was in a state of profound neglect, has been completely renovated and currently houses a hotel.

[4] The façade overlooking the canal is characterised by the round openings of the two noble floors and by a thick serrated cornice.