Pamplin City is a town in Appomattox and Prince Edward counties in the U.S. state of Virginia.

The Appomattox County portion of Pamplin City is part of the Lynchburg Metropolitan Statistical Area.

Previously, the High Bridge Trail ended at Heights School Road approximately one mile from the town.

In a partnership with The Virginia Department of Conservation and Recreation, Appomattox and Prince Edward Counties the Town has been able to have trail extended into the corporate limits and end within walking distance of the Main Street business district.

[7] According to the United States Census Bureau, the town has a total area of 0.3 square miles (0.8 km2), all land.

[12] About 53.7% of the population were below the poverty line, including 92.9% of those under the age of eighteen and approximately 0% of those 65 or over.