The Panache River is a tributary of the east bank of the Wetetnagami River flowing into Senneterre in the La Vallée-de-l'Or Regional County Municipality, in the administrative region of Abitibi-Témiscamingue, in Quebec, in Canada.

This river crosses downstream through the townships of Urban, Carpiquet, Muy and Effiat, successively.

The surface of the Panache River is usually frozen from early November to mid-May, however safe ice circulation is generally from mid-November to mid-April.

The confluence of the Panache River with the Wetetnagami Lake is located at: At different times in history, this territory has been occupied by the Atikamekw, Algonquins and Cree.

The name "Rivière au Panache" was officialized on December 5, 1968, at the Commission de toponymie du Québec, when it was created.