Charlotte Brotherson Shirley Ele Panama is a village in Lancaster County, Nebraska, United States.

In 1879, the Panama Cemetery Association was formed and raised funds to dig a well.

[4] Panama was originally founded one mile south of its present location but was moved in order to be closer to the railway.

[4] In 1888, the village was officially founded on land that was previously owned by Moses J. Mitton, John Forrest, and Gilbert F.

[4] According to the United States Census Bureau, the village has a total area of 0.28 square miles (0.73 km2), all land.

The racial makeup of the village was 98.4% White, 0.8% African American, 0.4% Asian, and 0.4% from two or more races.

21.1% of all households were made up of individuals, and 8.9% had someone living alone who was 65 years of age or older.

The racial makeup of the village was 98.81% White, 0.79% African American and 0.40% Asian.