Sprague is a village in Lancaster County, Nebraska, United States.

In 1865, a settlement called Centerville established a post office in the area, but never grew into a sustainable community.

[4][5] In 1894, a station named "Martell" was established and platted by the Rock Island Railroad nearby, but the village was never incorporated.

[5] In 1963, the Bluestem Conservation Dam was built in the area, creating a 325-acre lake.

[6] The lake increased numbers of retirement communities and recreational homes in the area, though it remains primarily rural and agricultural.

[4] According to the United States Census Bureau, the village has a total area of 0.10 square miles (0.26 km2), all land.

There were none of the families and 2.8% of the population living below the poverty line, including no under eighteens and 8.3% of those over 64.