The Panama Sea Frontier was a U.S. Navy command responsible during and shortly after World War II for the defense of the Pacific and Atlantic sea approaches to the Panama Canal and naval shore facilities in the Central America region.
On the west coast of the Americas, the responsibility of the Panama Sea Frontier was to protect Allied shipping in an ocean area extending from the Mexico-Guatemala border and out around the Galapagos, then to latitude 5 degree south.
On the eastern side of Panama, the sea frontier was responsible for the coastal areas from the Mexico-British Honduras boundary on the Yucatán Peninsula along latitude 18 degrees 5 minutes north to longitude 80 degrees 27 minutes west, and thence to Punta de Gallinas.
However, the prime responsibility of this sea frontier was the protection and defense of the Panama Canal and its operating equipment.
Anulfo Arias was replaced as president with the pro-Allied Ricardo Adolfo de la Guardia Arango, shortly before America was attacked at Pearl Harbor.