In total pancreatectomy, the gallbladder, distal stomach, a portion of the small intestine, associated lymph nodes and in certain cases the spleen are removed in addition to the entire pancreas.

[1] In recent years, the TP-IAT (Total Pancreatectomy with Islet Autotransplantation[2][3]) has also gained respectable traction within the medical community.

It is performed for a variety of reasons, including: The most common surgical procedure involving removal of a portion of the pancreas is called a pancreaticoduodenectomy.

Type 1 diabetes can be treated with careful blood glucose monitoring and insulin therapy.

[4] An experimental procedure called islet cell transplantation, most frequently the auto transplantation of islets isolated from the explanted pancreas into the portal vein, exists to help mitigate the loss of endocrine function following total pancreatectomy.