[2] In the episode, the boys try to capitalize on a sudden rise in Peruvian flute bands, unwittingly becoming players in a demonic being's plan to employ giant guinea pigs to attack the public.
The plan backfires when the head of U.S. Department of Homeland Security Michael Chertoff cracks down on all Peruvian flute bands, rounding them up and imprisoning them in Miami, with the boys also arrested in the process.
The boys express reluctance to go to Peru because a friend had been "raped" there, in reference to the film Indiana Jones and the Kingdom of the Crystal Skull which was parodied two episodes earlier in "The China Probrem".
IGN rated the episode a 6.2/10, stating "the show falls back on its old gimmicks of a national crisis with fast-paced scenes of men talking importantly about stupid things.
The sets included brief audio commentaries by Parker and Stone for each episode, a collection of deleted scenes, and two special mini-features, The Making of 'Major Boobage and Six Days to South Park.