Panther Burn is a census-designated place along U.S. Route 61 in northwestern Sharkey County, Mississippi, United States.

[4] It was first named as a CDP in the 2020 Census which listed a population of 115.

[9] The band Tav Falco's Panther Burns, which originated in nearby Memphis, takes its name from the community.

[10] Media related to Panther Burn, Mississippi at Wikimedia Commons

This Sharkey County, Mississippi state location article is a stub.