South Delta High School is a public high school in Rolling Fork, Mississippi (United States).

South Delta High is part of the South Delta School District; the district serves all of Sharkey County, including the towns of Rolling Fork, Anguilla, and Cary, as well as the unincorporated areas of Delta City, Nitta Yuma, and Panther Burn.

[4] It also serves most of Issaquena County, including the town of Mayersville, the unincorporated area of Valley Park, and most of the unincorporated area of Grace.

There were a total of 374 students enrolled in South Delta High during the 2006–2007 school year.

The racial makeup of the school was 97.06% African American, 2.41% White, and 0.53% Hispanic.