Panthera works in partnership with local and international NGOs, scientific institutions, corporate partner and government agencies to develop and implement range-wide species conservation strategies.

Jaguar survival and health depends on a network of corridors that span the continent, while past efforts focused on developing distinct sanctuaries.

In August 2010, in Belize, it worked with the government to create the Labouring Creek Jaguar Corridor Wildlife Sanctuary, with more than 7,000 acres (28 km²) of land.

In early 2010, Panthera signed a deal with the Colombian government to protect and develop the area where the Central and South American jaguar corridors converge in Colombia.

They are working with local ranchers to find benign ways to protect their cattle, rather than the typical approach of shooting the jaguars.

In the Northwest, their Olympic Cougar Project represents an important and exciting partnership between Panthera and six indigenous tribes, led by the Lower Elwha Klallam Tribe, to study and protect pumas in the dense coniferous forests, glacier-clad mountains and rugged coastlines of Washington’s stunning Olympic Peninsula.

Panthera CEO Alan Rabinowitz helped bring together representatives from the Kachin Independence Army and the Myanmar government to make the expansion possible.

Panthera CEO Alan Rabinowitz helped bring together representatives from the Kachin Independence Army and the Burma government to make the expansion possible.

[22] Panthera's Snow Leopard Program is studying the species in Mongolia, and surveying new regions where the animals are likely to live, but have not yet been discovered.

In South Africa, the Sabi Sands protected area, bordering the Kruger National Park, is a long-term leopard research site and one of Panthera’s flagship projects.

The knowledge generated from this work is critical to informing local wildlife management and broader conservation policy across the leopard range.

Panthera Gabon is currently working on a countrywide leopard survey and helping the Gabonese government and ANPN identify gazelle wildlife movement corridors in order to secure and connect populations.

[35] Panthera also works on initiatives in southern Africa that provide synthetic wild cat furs to communities in place of traditional garb.