The station services the colonias (neighborhoods) of Ampliación Adolfo López Mateos, Aviación Civil, and Pantitlán, and is named after the last one.

The station facilities offer partial accessibility for people with disabilities as there are elevators, wheelchair ramps, tactile pavings, and braille signage plates.

Between December 2023 and September 2024, the Line 9 station was closed for releveling of the elevated bridge due to continued subsidence.

The station serves three colonias (neighborhoods), Ampliación Adolfo López Mateos, Aviación Civil, and Pantitlán.

During the Aztec era, the area, formerly part of Lake Texcoco, was marked with flagpoles to warn canoeists of dangerous currents.

The exit for Line 1 is located to the west and provides access to Avenida Miguel Lebrija and Calle Alberto Braniff in Colonia Aviación Civil, Venustiano Carranza.

The western exit can be found along Avenida Río Churubusco in Colonia Ampliación Adolfo López Mateos, Venustiano Carranza.

The eastern exit is located at the corner of Avenida Miguel Lebrija and Calle 2ª Cerrada de Río Churubusco in Colonia Pantitlán, Iztacalco.

The northern exit is at the corner of Avenida Río Churubusco and Calle Talleres Gráficos in Colonia Ampliación Adolfo López Mateos, Venustiano Carranza.

[10] Pantitlán is also the nearest metro station to Terminal 2 of the Mexico City International Airport, situated around 500 meters (1,600 ft) away.

[15] An eastward extension toward Pantitlán opened on 22 August 1984, operating westward towards Observatorio metro station and connecting Lines 1 and 5.

[14] Pantitlán is an underground metro station[19] with an interstation tunnel to Zaragoza measuring 1,320 meters (4,330 ft).

[25] Excélsior reported in July 2024 that all the modernized stations had leaks of varying dimensions, despite authorities having stated they would seal them during the repairs.

[26] Cometro built the line and its first section was opened on 19 December 1981, with operations extending toward Consulado station.

[13] Empresas ICA built the line and it was opened on 12 August 1991, operating towards La Paz station, in the municipality of the same name of the State of Mexico.

Allegory to Mexico City and the Collective Transport System), painted by José Luis Elías Jáuregui.

According to him, he was inspired by the country's history, painting various elements that symbolize it, such as the Popocatépetl and Iztaccíhuatl volcanoes, an eagle devouring a snake (a reference to the national coat of arms), a pyramid, and a Mestiza holding a white dove.

The acrylic-on-canvas artwork, which is 9 m (30 ft) wide, honors the metro workers by featuring four train models used by the system.

[45]: 48:00–52:48 Because the bridge shoring did not resolve the issues and the sinking persisted, metro authorities announced in September 2023 that three Line 9 stations—Pantitlán, Puebla, and Ciudad Deportiva—would be closed.

[52][53] Platforms M, N, O, P, Q, R, S, and T at the CETRAM were closed on 11 October 2021 due to structural failures detected in the station's basement, which houses out-of-service trains.

A police officer rappeled down to rescue him, but the weight of both individuals caused the rope to break, resulting in a fall of approximately 8 meters (26 ft).

[55][56] According to the data provided by the authorities, all of Pantitlán's platforms rank among the busiest of the system's 195 stations when considered individually.