For Muccino, Paolo Buonvino wrote the scores for some of the movies that would not only become colossal hits at the Italian box-office but generational phenomena, considered modern classics: Ecco fatto (1998); Come te nessuno mai (But forever in My Mind) (1999), L'ultimo bacio (The Last Kiss) (2001); Ricordati di me (Remember Me, My Love) (2003); Baciami ancora (Kiss Me Again) (2010); and the American production of Fathers & Daughters (2015), starring Russell Crowe, Amanda Seyfried, Kylie Rogers alongside Jane Fonda and Octavia Spencer.

In 2020, he composed the score for the faith-based drama film Fátima[5] directed by Marco Pontecorvo, starring Harvey Keitel and Sônia Braga alongside Joaquim de Almeida, Goran Visnjic, and Lúcia Moniz.

A special guest star on the score is Italian opera tenor Andrea Bocelli who sings the movie's lead theme "Gratia plena".

The disc features original interpretations by Jovanotti, Mahmood, Gianna Nannini and Diodato recorded during the 2020 edition of the Notte della Taranta.

In 2021, the Biennale Musica di Venezia commissions him a project that sees the light of day in September 2022 at the Teatro alle Tese in Venice, entitled "Çiatu";[9] a concert for reciting voices, three disklaviers and electronic music, with the art installation by Irma Blank,[10] performed by the Parco della Musica Contemporanea Ensemble orchestra,[11] conducted by Tonino Battista.