He developed and improved quantitative methods for the synthesis of large carbonyl clusters, such as thermal degradation and redox condensation.

Today these methods are still the main approaches to the synthesis of high nuclearity heterometallic clusters.

He was also assistant of the Nobel laureate Giulio Natta, together with he took an active part on the development of polypropylene polymer synthesis pathway.

[1] Every year, as a tribute of his fundamental work, the "Paolo Chini Memorial Lecture" is awarded to a scientist who have excelled in organometallic chemistry and in catalysis.

The prize is sponsored and organized by the "Chini Foundation", administered by the Società Chimica Italiana (Italian Chemical Society).