He is best known for Superman 51, which consisted of the artist running with 51 blocks tied to his back on the West Side Highway until exhaustion.
In 1982, Papo Colo with Jeanette Ingberman, founded Exit Art,[4][5] an internationally known cultural center in New York City.
He has won numerous awards including The New York Times Best Inaugural Show by an Alternative Art Space for his exhibition Exit Biennial: Reconstruction[8] Additionally, REACTIONS, an international response to 9/11 conceived by Papo Colo, was acquired by The Library of Congress for its permanent collection[9] Jeanette Ingberman died August 24, 2011, from complications of leukemia.
Besides being the curator and cultural producer of Exit Art, Papo Colo has organized over 100 shows in which he was also the exhibition and graphic designer.
[10] In 1991 Papo Colo received a Guggenheim Fellowship, an award that is bestowed upon individuals who have demonstrated distinguished accomplishment in the past and potential for future achievement.