In June 2018, Paradigm was founded by Coinbase co-founder Fred Ehrsam and Sequoia Capital Partner Matt Huang.

[4] In January 2021, Paradigm and Sequoia Capital invested $1.15 billion in Citadel Securities making them the first outsider investors in the firm.

Uniswap investors Paradigm, Andreessen Horowitz, and Union Square Ventures were also included in the lawsuit for developing and promoting the platform.

[4][8] In February 2023, Paradigm, Sequoia Capital, Thoma Bravo were sued in a class action for hyping the legitimacy of FTX.

[8] In May 2023, The Block reported Paradigm's website homepage completely removed any mention of Web3 or crypto and had changed to "research-driven technology," which included artificial intelligence (AI).

[10] In September 2023, Paradigm submitted an amicus curiae arguing that the U.S. Securities and Exchange Commission had overstepped its authority when it filed charges against Binance in June that year.