[2] Hignia Giosa became the first president of the newly established Paraguayan Paralympic Committee (Spanish: Comité Paralímpico Paraguayo).

[3] Paraguay was one of five countries to make their first appearance in the 2020 Summer Paralympic Games; the others were Bhutan, Grenada, Maldives and Saint Vincent and the Grenadines.

[4] President of Paraguay Mario Abdo Benítez met with the athletes at the start of August where he handed over the national flag.

[11][12] Guide: Victor Duarte Rodrigo Fabián Hermosa Ayala[b], aged 18 became the second Paraguayan athlete to compete at the Paralympics.

[15] In the heats of the 50 metre freestyle S9 race on 29 August 2021, he beat both his opponents but did not qualify for the final as he was not in the top eight overall.