Human parechoviruses may cause gastrointestinal or respiratory illness in infants, and they have been implicated in cases of myocarditis and encephalitis.

[11] Human parechoviruses cause mild, gastrointestinal or respiratory illness, but have been implicated in cases of myocarditis and encephalitis.

[12][13] Parechovirus B has been proposed as a zoonotic virus, associated with diabetes and intrauterine fetal death in humans.

Those numbers include a set of identical triplets from central Wisconsin, who contracted the virus and were diagnosed nearly two months later after a flurry of tests, as this was the first known case in those health systems.

[19] The 2014 outbreak is a higher number than expected, and is thought to be linked to maternal-fetal transmission.