This hospital provides general and acute care, as well as a comprehensive range of clinical specialties and sub-specialties.

[3] The new owners refurbished and modernised the existing facilities, and renamed it Saint Mark's Hospital.

In 1977, Dr Yahya Cohen together with American Medical International (AMI) entered a joint venture with the former to form Saint Mark's AMI Pte Ltd.[3] Saint Mark's Hospital further expanded with a purchase of a 40,000 sqft site adjacent to the existing building in 1982.

It is an event designed for children living in the East to role-play as doctors in a real hospital setting.

In 2013, Pathway Genomics Corporation, a San Diego–based clinical laboratory that offers genetic testing services internationally, partnered with Parkway Laboratory Services Ltd, an ancillary service of Parkway Pantai Limited to offer Pathway Fit, a comprehensive saliva-based nutrigenetic test that reports on a patient's genetic propensity for diet, nutritional needs, metabolic health factors and food reactions.

[7] Parkway East Hospital adopted the Electronic Medical Records (EMR) and implemented it in 2015.

It is implemented with the intention of reducing paper wastage by having a centralized storage for patients' details and medical records.