This nocturnal species is found in karstic dry forests at night, and is known to dwell in caves during the day.

[2] The head has an immaculate tan color and posterolaterally bordered by light lines, differing from the rest of the body.

[2] Later expeditions have made dozens of observations of this gecko inhabiting a cave throughout the daytime, always in areas of complete darkness away from the entrance.

[4] Like most geckos, Paroedura tanjaka is an insectivorous species and primarily preys upon small arthropods, hunting them at night in the karstic forests.

Both troglobitic invertebrates and nocturnal species resting to avoid predation or daytime heat (including the moth Cyligramma duplex) are present in the caves, and likely are part of the lizard's diet.

[4] This lizard is known to fall prey to snakes, as one specimen (UMMZ 221997) was found inside the stomach of a Lycodryas gaimardi.

Though the species is reportedly abundant at Bemaraha, there is continuing decline of mature individuals, and its habitat is threatened by increased fire intensity and logging.

Conservative measures are not in place for the species itself, but both its known localities (Bemaraha and Namoraka) are national parks and thus protected areas.