He played college football for the Auburn Tigers and was selected by the Green Bay Packers in the second round of the 2008 NFL draft.

Lee won Super Bowl XLV with the Packers over the Pittsburgh Steelers.

Lee finished his senior season with 70 tackles, seven pass breakups, three interceptions and two fumble recoveries.

As a junior Lee shared right cornerback duties with Jonathan Wilhite, starting four of 12 games he played in.

He started all year at right cornerback where he had a career-high 55 tackles (40 solos), which ranked sixth on the team.

He also averaged 25.8 yards on 11 kickoff returns, caused a fumble, broke up 10 passes and intercepted four others.

Pat Lee was bothered most of the season by a lingering knee injury and was finally placed on injured reserve on December 5, 2008.

At the end of the 2010 season, Lee and the Packers appeared in Super Bowl XLV against the Pittsburgh Steelers.