He played in Major League Baseball from 1992 to 2003 with the Minnesota Twins, Boston Red Sox, New York Mets, Texas Rangers, Chicago Cubs and Pittsburgh Pirates.

[1] Mahomes was only 5 ft 9 in (1.75 m) as a high school junior but earned all-state honors as a football quarterback and averaged 30 points per game in basketball, nonetheless.

[1] Drafted in the sixth round in June 1988, Mahomes began his professional career with the Elizabethton Twins that same year as a starting pitcher.

He made the team out of spring training, and started the sixth game of the season, on April 12 against the Texas Rangers, pitching six innings and getting a no decision.

The Twins traded Mahomes to the Red Sox on August 26, 1996, in exchange for a player to be named later (which turned out to be pitcher Brian Looney).

[5] Mahomes pitched a total of 21 games (all in relief) during the 1996 and 1997 seasons with Boston, registering a 6.85 ERA with 3–0 record and 11 strikeouts in 22+1⁄3 innings.

Mahomes made four relief appearances during the postseason, recording a 2.25 ERA in eight innings pitched while striking out four, as the Mets lost to the Atlanta Braves in the NLCS.

On August 24, the Toronto Blue Jays signed him, and he appeared in three games for the Syracuse Chiefs before becoming a free agent at the end of the season.

Mahomes signed with the Southern Maryland Blue Crabs of the Atlantic League in 2008, but only appeared in two games for them before returning to Sioux Falls.

He has two sons with his ex-wife:[7] Patrick II, who is a quarterback for the Kansas City Chiefs[8] and Jackson, who is a social media influencer.

[9] Pat received attention for smoking cigars dedicated to the opposing teams' quarterbacks his son has defeated in AFC Championship Games.

[18] On July 12, 2024, court documents obtained by TMZ revealed that Mahomes had also been driving with a driver's license that was invalid due to his ongoing DWI case.

[16][17] On August 27, 2024, Mahomes pled guilty in the Smith County court in Tyler, Texas to his third DWI charge.