Patch Grove is a village in Grant County, Wisconsin, United States.

According to the United States Census Bureau, the village has a total area of 0.39 square miles (1.01 km2), all of it land.

26.8% of all households were made up of individuals, and 8.5% had someone living alone who was 65 years of age or older.

21.5% of all households were made up of individuals, and 15.4% had someone living alone who was 65 years of age or older.

About 12.1% of families and 13.0% of the population were below the poverty line, including 24.3% of those under the age of eighteen and 16.7% of those 65 or over.

The River Ridge High-Middle School is located in Patch Grove on US-18 / Wis-133.