Path of Unreason is a science fiction novel by American writer George O. Smith.

It was published in 1958 by Gnome Press in an edition of 5,000 copies, of which only 3,000 were bound.

The novel concerns a physicist who is trying to explain the mysterious "Lawson Radiation" while his researches drive him insane.

Galaxy reviewer Floyd C. Gale gave Path a negative review, rating the novel with two stars out of five and writing that "it is a story that Smith evidently had a lot of fun writing but that the reader will find more difficult to enjoy.

This article about a 1950s science fiction novel is a stub.