The film stars Uttam Kumar, and Suchitra Sen[8] in leading role and others artists like Shishir Batabyal, Anil Bhattacharya, Mihir Bhattacharya, Chhabi Biswas, Bharati Devi, Chandrabati Devi, Jahar Ganguli, Anup Kumar, Shyam Laha, Gopal Majumdar, Chitra Mandal, Sova Sen, and Kamala Mukherjee in the supporting roles.
Mallika helps Jayanta by giving him her mother's jewellery in order to fund his study of medicine in Europe.
Things change when Jayanta comes back to find Mallika in a psychotic vegetative state resulting out of the anxiety and depression of being estranged from him.
The Times of India wrote With their sheer charisma and chemistry, Uttam-Suchitra used to beat any other on-screen couple hollow.
Their classic romantic films together are a treat to watch even today and ‘Pathey Holo Deri’ seems to be no exception.