An updated version, Pathologic Classic HD, was developed by General Arcade,[2] published by Good Shepard Entertainment, and released in October 2015.

The player can select one of the three playable healers listed by their honorifics: The Bachelor (Daniil Dankovsky), Haruspex (Artemy Burakh), and The Devotress, Klara (later re-translated as "The Changeling, Clara").

Completing main quests is essential to uncovering the secrets of the town, as characters who would otherwise reveal information later in the game can fall ill from the plague early.

The game's fluctuating economy represents the harsh forces of supply and demand in an isolated, disease-ridden town.

Each character has an assigned group of NPCs - their "Bound" - which they are tasked with keeping safe by completing the main quest every day.

[3] The game was announced by Russian publisher Buka Entertainment on 30 March 2004, intending to release in the last quarter of the year.

[6][7][8] A German version was published by Frogster Interactive Pictures on 20 April 2006 after being released to manufacturing earlier that month.

[14] However, its reception in English-speaking countries has been mixed, being both praised for its atmosphere and concept, while panned for its poor translation, outdated graphics and slow-paced gameplay.

[15] They later confirmed the remake's development in July 2014 and launched a Kickstarter crowdfunding campaign that September,[16][17] sought to raise US$250,000.

[19][20] This remaster introduced upgraded visuals, fixed bugs, re-recorded dialog, and a re-translated English script.