After starting at Canon Yaoundé and spending time on the fringes of France's Le Mans, he had brief spells in Switzerland, Spain, and Romania, where he died after collapsing in a match for Dinamo București.

On 4 July 2009, he signed a three-year deal with Le Mans FC,[2] and was initially assigned to the reserve squad in the Championnat de France Amateur.

Ekeng played his first match as a professional on 20 August 2010, coming on as a second-half substitute in a 0–2 home loss against LB Châteauroux for the Ligue 2 championship.

[7] He made his La Liga debut on 30 August, replacing Aritz López Garai in the 74th minute of a 1–1 home draw against Celta de Vigo.

[13] On 7 January 2015, Ekeng made his full squad debut, coming on as a 57th-minute substitute for Franck Kom in a 1–1 friendly draw against DR Congo in his hometown's Stade Ahmadou Ahidjo.

[12] Nine days after his death, his funeral was held in his hometown, attended by past and present Cameroonian internationals and the nation's sports minister; Ekeng's brother said at the ceremony that he was comforted by his having led a selfless life.

[17] After Ekeng's death, all matches in Romania that weekend were postponed, and Dinamo's cup final against CFR Cluj was moved a week later than scheduled.