Graham took control of John's plantation that Ann inherited after he died and continued to cultivate it with silkworms, giving it the name Mulberry Grove.
When the ban on slavery was lifted in Georgia, Graham began to primarily grow rice using enslaved laborers.
The plantation would later be owned by Major General Nathanael Greene, and was the location where Eli Whitney invented the cotton gin.
In 1745, Graham was appointed to a council with two other future colonial governors of Georgia: William Stephens and Henry Parker.
[2] While serving as governor, Graham planned a settlement in Hardwick, Bryan County, Georgia named Georgetown in honor of reining monarch George II.