[6] Kane was inadvertently featured in the background of Sylvain Turgeon's 1994-95 Pinnacle trading card while attending a Sabres' game as a child with his father.

[9] His father allowed Kane to practice stick-handling and shooting in their house's basement, going as far as to set up a miniature rink that featured nets and boards.

[10] Donnie Harkins, the head coach of the Honeybaked 16U AAA hockey club, personally recruited Kane to join his team in Michigan after watching him play in a tournament.

He resided with former NHL player Pat Verbeek while living in Detroit, whom Kane regards as a mentor and one of his primary reasons for relocating.

[8] He reflected on the US NTDP by commenting, "The program really focuses on improving your body, you get a lot of practice time and you really learn how to play the game and how to treat yourself.

[17] Kane won the Emms Family Award for the OHL rookie of the year,[14] and was the runner-up to John Tavares for the Red Tilson Trophy as league MVP.

On June 12, 2008, he received the Calder Memorial Trophy, awarded to the NHL's rookie of the year, finishing ahead of teammate Jonathan Toews and Washington Capitals forward Nicklas Bäckström.

[27] He finished his first NHL playoffs with nine goals, five assists for 14 points in 16 out of 17 games as the Blackhawks were eliminated in the Western Conference Finals by the defending Stanley Cup champion and second-seeded Detroit Red Wings.

On June 9, 2010, in game six of the Finals, Kane scored the overtime winner when he shot the puck under the pads of Philadelphia Flyers goaltender Michael Leighton and into the net, winning the Blackhawks the Stanley Cup.

[32] It also made Kane the youngest player in NHL history to score a Stanley Cup-winning goal in overtime; that record previously belonged to Bobby Orr in 1970.

[37] On April 10 in the last game of the season in a 4–3 loss to the Detroit Red Wings, Kane recorded his 200th career assist on a Michael Frolík goal.

Kane revealed he underwent surgery to repair a broken wrist he suffered towards the end of the season that was only discovered during the following offseason after the Blackhawks first round playoff exit.

[40] In the first round of the 2012 playoffs, Kane was held goalless with four assists and points recorded as the Blackhawks would go on to lose the series against the third-seeded Phoenix Coyotes in six games.

Shortly after the Blackhawks elimination from the 2012 playoffs, Kane was criticized after photos surfaced showing him in an intoxicated state at a Cinco de Mayo block party in Madison, Wisconsin during the ensuing offseason.

[61] Following the 2015 off-season departures of Brandon Saad and Brad Richards to the Columbus Blue Jackets and Detroit Red Wings respectively, the Blackhawks signed rookie winger Artemi Panarin and traded for veteran center Artem Anisimov to join Kane on the second line for the 2015–16 season.

On April 1, 2016, Kane reached the 40-goal mark for the first time in his NHL career when he scored a late goal in the second period of a 5–4 overtime victory against the Winnipeg Jets.

He finished the season playing in all 82 contests with 34 goals, 55 assists 89 points, finishing second in the NHL behind Edmonton Oilers captain Connor McDavid and tied with Pittsburgh Penguins captain Sidney Crosby and was named a finalist for the Ted Lindsay Award for the second straight season and second time in his career which was eventually given to McDavid.

During the ensuing off-season, Panarin was traded to the Columbus Blue Jackets in a four-player deal in exchange for Brandon Saad returning to the Blackhawks.

[78] The 2018–19 season saw Kane record (44) goals, along with a career high in assists (66) and points (110) while playing with Dylan Strome and Alex DeBrincat on the teams second line.

[79] Kane was named a finalist for the Ted Lindsay Award for the third time in his career which would ultimately go to Tampa Bay Lightning forward Nikita Kucherov.

In doing so, Kane became the fourth player in Blackhawks franchise history to reach that mark with the club, along with Stan Mikita, Bobby Hull and Denis Savard.

[91] The Blackhawks and Kane parted ways at the trade deadline, with the team opting to acquire future draft capital and initiate a full-scale rebuild.

[96] Following the Rangers' first-round playoff exit, Pat Brisson announced that Kane underwent successful hip resurfacing surgery on June 1, and would miss from four to sixth months while recovering.

[103][104] Red Wings general manager Steve Yzerman commended Kane's contributions to the team, stating "He’s like a wizard with the puck -- his skill, his sense, his calmness in high-pressure situations and in the danger areas.

[130] During the first round in the 2014 Stanley Cup playoffs, Kane performed a goal celebration after scoring the game winner against the St. Louis Blues, where he pretended to use a payphone.

According to a police report, Kane was apprehended around 5:00 a.m. after allegedly punching cab driver Jan Radecki when he claimed to not have proper change for their trip fare.

On August 27, Kane and cousin pleaded guilty to noncriminal disorderly conduct charges, and were both given conditional discharges, avoiding any penalties if they stayed out of trouble for a year, and also ordered to apologize to Radecki.

[157] On August 6, 2015, the Buffalo News reported that Kane was the subject of a sexual assault investigation by police in Hamburg, New York, in connection with an incident that allegedly occurred the previous weekend.

[158] The Erie County District Attorney's Office later declined to press charges against him, stating that the complainant's allegation was not sufficiently substantiated by credible evidence.

[159] Prior to office's determination that it would not press charges, the mother of his accuser orchestrated a hoax in which she attempted to mislead the public into an impression that critical evidence had been tampered with.