His six sisters—Jane, Barbara, Margaret, Elizabeth, Anne, and Charlotte — were notable artists whilst his younger brother, James, was a prominent engineer who invented the steam hammer.
[1] As a teenager Nasmyth lost the use of his right hand following an accident, forcing him to learn how to paint with his left.
Much of Nasmyth's work, a great deal of which is undated, depicts his native Scotland, which he continued to paint even after moving to London in 1810.
Like his father, he was heavily influenced by the Dutch masters of the 17th century, particularly Meindert Hobbema and Jacob van Ruysdael (a large number of works by both men were displayed in London galleries during Nasmyth's lifetime).
Nasmyth died of pneumonia-like symptoms, which he contracted shortly after painting a scene just outside London.