Patterson High School is a high school in unincorporated St. Mary Parish, Louisiana, United States, near the city of Patterson.

It is a part of the St. Mary Parish School Board.

Patterson High competes in the LHSAA in the 3A classification in all of the following varsity sports: baseball, basketball (boys and girls), cross country (boys), football, golf, softball, swimming, tennis, track and field, and volleyball.

On January 15, 2009, Kenny Hilliard, a sophomore running back at Patterson High was named ESPN RISE Sophomore Player of the Year.

[2] Patterson High was named a Blue Ribbon Schools in 2006 in which former principal, Michael Brocato, and head of the math department, Cathie Vernon, traveled to Washington D.C. to accept the award.