Paxico is a city in Wabaunsee County, Kansas, United States.

[4] Paxico was originally called Strong Mill, and under this former name was established in 1879 about one mile east of the present town site.

[5] A post office was set up and named Paxico, in honor of the Potawatomi medicine man Pashqua.

[5][6][7] When the railroad was built though the area in 1886, the town moved in order to be alongside it.

[5] In 1887, the Chicago, Kansas and Nebraska Railway built a main line from Topeka through Paxico to Herington.

According to the United States Census Bureau, the city has a total area of 0.14 square miles (0.36 km2), all land.

The 2020 United States census counted 210 people, 81 households, and 55 families in Paxico.

23.5% of households consisted of individuals and 12.3% had someone living alone who was 65 years of age or older.

24.7% of all households were made up of individuals, and 7.1% had someone living alone who was 65 years of age or older.

About 5.8% of families and 10.3% of the population were below the poverty line, including 9.5% of those under the age of eighteen and 8.7% of those 65 or over.

The community is served by Wabaunsee USD 329 public school district.

USD 329 was formed by school unification that consolidated Alma, Maple Hill, McFarland, and Paxico.