Prior to 1818, the western corner of what became Gwinnett County was Creek and Cherokee territory, and it was illegal for white families to settle there.

In the late 1960s, Paul Duke developed the idea of creating Peachtree Corners, a planned community to be constructed in the area that was once known as Pinckneyville.

[9] Initial residents of the technology park included GE, Scientific Atlanta (now part of Cisco Systems), and Hayes Microcomputer Products.

[13] A city of Peachtree Corners was again proposed by the UPCCA in 2005, but efforts were abandoned after a straw survey of some residents seemed to indicate that the majority did not support incorporation.

[14] In 2010 the UPCCA again pursued the incorporation of Peachtree Corners[15] after a failed attempt by the city of Norcross to annex a portion of Technology Park Atlanta.

The company purchased a 50,000 square foot office building on Spalding Drive for logistics, accounting and customer service operations.

In 2017 it merged with Hapag-Lloyd, keeping its headquarters in Peachtree Corners, investing an additional $5.5 million, and adding 363 new jobs to expand its offices.

[34][35] In August 2021, the NASDAQ-100 and S&P 500 company, Intuitive Surgical announced its expansion of its Peachtree Corners facility, building an additional $600 million dollar, 750,000 square foot, net zero carbon footprint, medical campus in the city, adding 1,200 new jobs and adding to the cluster of many medical, biomedical, biopharmaceutical, and health information technology companies that are in Peachtree Corners.

[35][36] Soliant Health, a leading provider of specialized healthcare and education staffing services to hospitals and schools around the nation, expanded its Peachtree Corners headquarters to 83,000 square feet.

[37][38][39][40][41][42][43] The Harlem Globetrotters are headquartered in Peachtree Corners as well as the Southern Section of the United States Tennis Association (USTA).

[50] The facility features a 25,000 square foot Innovation Center and 3-mile autonomous vehicle test track and provides developers the ability to build and test such things as autonomous vehicles, robotics, industrial drone applications, mixed reality training and entertainment, remote medical care, personal health and fitness wearables, and other technologies.

[51] Jacobs Engineering Group, Peachtree Corners, Delta Air Lines, Bosch, Cisco Systems, and Qualcomm are also jointly working to deploy smart system technologies in the city through technology that connects vehicles and infrastructure, focusing initially on roadside infrastructure, traffic management, and road safety.

[50][36] Further, Peachtree Corners is host to the Vehicle-to-everything (V2X) conference which involves development of intelligent transport systems including Vehicle-to-vehicle (V2V), Vehicle-to-infrastructure (V2I), and Vehicle-to-Pedestrian (V2P) communications and includes biometric technology, managing cities autonomously, and developing highway systems to make transportation safer, reduce traffic congestion, and reduce the environmental impact of automobiles and other road vehicles.

[52][45] Curiosity Lab was named winner in IDC Government Insights’ Fourth Annual Smart Cities North America Awards for Transportation.

[53] The French-American Chamber of Commerce moved its operations from the Consulate General of France in Atlanta to office space within the Innovation Center at Curiosity Lab.

[54] Funded by the city, Peachtree Corners has produced a non-profit business incubator affiliated with the Technology Development Center at Georgia Tech as part of the city's Curiosity Lab that provides for software and hardware technology startups, providing these companies with the support they need to launch new products and grow.

[57][58] Other annual events include the "Peachtree Corners Festival" that includes arts and crafts, live music, shows, and food, as well as the "Holiday Glow on the Town Green" evening event featuring live choral performances and the lighting of the great tree and 6-foot Menorah.

[69] Peachtree Corners is home to the headquarters for the Southern Section of the United States Tennis Association (USTA).

[71] A thrust arch style 14-foot wide walkway pedestrian bridge crossing Peachtree Parkway features two elevators and two sets of stairs and connects the Town Center and The Forum.

[99] Nearby is another charter school, the New Life Academy of Excellence (K-8th grade) that has a bilingual English and Chinese education program.

[64] As part of the Metro Atlanta area, the city's primary network-affiliated television stations are WXIA-TV (NBC), WANF (CBS), WSB-TV (ABC), and WAGA-TV (Fox).

[109] The former site of BJ's Wholesale Club was used as the set of the 2012 movie The Watch starring Ben Stiller, Vince Vaughn, and Jonah Hill.

[110] A home on Fitzpatrick Way in Peachtree Corners was used as a filming location for the 2015 movie Barely Lethal starring Sophie Turner, Jessica Alba, and Samuel L. Jackson.

[113] Peachtree Corners has implemented support for electric vehicles having installed one of the State of Georgia's largest electric vehicle charging facilities that provides charging without cost to users, and installing the country's first roadway surface solar panel system to support it, with plans for further expansion of roadway solar power collection and charging facilities and including solar power for existing infrastructure across the city by installing other types of panels that may include sidewalk, bike lane, and other surface collectors.

[116] Peachtree Corners has its own smartphone app, "CornersConnect", for the use of citizens and visitors to keep up with events, dining, entertainment, public parks, bus routes, city information, and news, and to help users pay their water bill, county property taxes, to register to vote, and to photograph and report areas that need improvement across the city.

[122] Peachtree Corners is served by Gwinnett County Fire and Rescue Department's Stations 1, 4, 11, and 19, and is served by the West Precinct of the Gwinnett Police Department that includes two six-member Response Teams that are responsible for responding to any issues or concerns that arise in Peachtree Corners.