It is a coastal island belonging to the Cacheu Region and the Caió sector.

The chiefs of Pecixe tended to ally with the Papel chiefdoms in the 19th century to the east instead of their northern Manjak neighbors.

However, this proved to be short lived: in 1897, the Chiefdom of Pecixe joined a successful rebellion led by Chief of Pandim with several other chiefdoms against Bassarel, leaving the kingdom with half its previous territory.

The island was conquered by Portuguese forces during the Pacification Campaign in the early 20th century.

[5] Under Portugal, Pecixe was administered jointly with Jeta and Caió until the 1940s, when the island became its own district to better exploit its natural resources.