[1][3] Pedra Branca do Amapari is bordered by the municipalities of Oiapoque to the north, Serra do Navio to the east, Porto Grande to the southeast, Mazagão to the south, and Laranjal do Jari to the west.

[1] The municipality contains 12% of the 806,184 hectares (1,992,120 acres) Rio Iratapuru Sustainable Development Reserve, created in 1997.

[5] The municipality of Amapari was originally explored by members of the Saramaka, a Maroon group from Suriname, who searched for gold in the area.

[6] Amapari supports the small-scale production of rice, corn, beans, and cassava for the domestic market.

Gold mining has become a major part of the economy, and resulted in a steep population growth.