It is mostly found near a fresh water supply when it can lay its eggs or in dense underbrush, leaf litter, or other fallen object covering the ground.

June–October is the areas monsoon/rainy season, while in December–May there are "trade winds" which bring little rainfall, making it harder for the frog to find suitably wet places to breed.

It will eat most of the insects found in Mindanao, it will also consume snails, spiders, worms, and occasionally frogs that are smaller than itself.

[4] The Mindanao horned frog is currently listed as vulnerable on the endangered species scale because its distribution is rather fragmented; it covers an area of less than 20,000 km2 and is continuously shrinking due to deforestation.

In addition to the birds, other animals such as snakes and fish prey on the frog and its young, whilst pets, such as cats and dogs, also pose a threat.