It encompasses the boroughs of Centre Hall and Millheim, Pennsylvania, as well as the townships of Potter, Gregg, Penn, Miles, and Haines.

According to the Pennsylvania Budget and Policy Center, 30.4% of the district's pupils lived at 185% or below the Federal Poverty Level [1] as shown by their eligibility for the federal free or reduced price school meal programs in 2012.

[11] Special education, criminal background check processing for prospective employees and professional development for staff and faculty are provided by district employees and the Central Intermediate Unit CIU10.

Occupational training and adult education in various vocational and technical fields were provided by the district and the Central Pennsylvania Institute of Science and Technology, which is located in Pleasant Gap.

Penns Valley Area School District offers a wide variety of clubs, activities and an extensive sports program.