The length of this route serves as a shortcut for through traffic on US 6 creating a bypass of Scranton and Clarks Summit.

PA 107 is a two-lane undivided road that runs through mostly rural areas in the northern part of Lackawanna County.

The route heads through forested areas, curving north-northeast and passing under Norfolk Southern's Sunbury Line.

The road crosses into Nicholson Township and heads northeast through more wooded areas with some homes, turning east and passing to the south of Lake Sheridan.

The route passes over the Lackawanna River and a Delaware-Lackawanna Railroad line, heading into wooded areas and crossing back into Mayfield.

PA 107 comes to its eastern terminus at an interchange with the US 6 freeway on the border of Mayfield and the borough of Archbald.