Perazine (Taxilan) is a moderate-potency typical antipsychotic of the phenothiazine class.

It is quite similar to chlorpromazine, and acts as a dopamine antagonist.

A 2014 systematic review compared it with other antipsychotic drugs: Phenothiazine-10-propionitrile [1698-80-2] (1) is treated with a mixture of acid and alcohol giving Methyl phenothiazinepropionate, CID:368244 (2).

Reduction of this last by means of diborane yields Perazine (5).

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